Palmer And Bhakdi On The Pfizer Animal Study

I'm pasting in the introduction and conclusion of a paper by Michael Palmer and Sucharit Bhakdi for doctors4covidethics.org. The full 17 page paper can be found here. Thanks to the commenter who provided the link.

I would call particular attention to the conclusions regarding the possible effects of repeated injections.

The Pfizer mRNA vaccine: pharmacokinetics and toxicity

Michael Palmer, MD and Sucharit Bhakdi, MD

July 23rd, 2021

Abstract

We summarize the findings of an animal study which Pfizer submitted to the Japanese health authorities in 2020, and which pertained to the distribution and elimination of a model mRNA vaccine. We show that this study clearly presaged grave risks of blood clotting and other adverse effects. The failure to monitor and assess these risks in the subsequent clinical trials, and the grossly negligent review process in conjunction with the emergency use authorizations, have predictably resulted in an unprecedented medical disaster.

1 Introduction and background

As with any drug, a key consideration for the toxicity of the COVID mRNA vaccines

is where exactly in the body they end up, and for how long they will stay there.

Such questions, which are the subject of pharmacokinetics, are usually thoroughly

investigated and during drug development. Initial studies on pharmacokinetics and

also on toxicity are carried out in animals. If the outcome is favourable, similar

experiments will be performed on a small number of human volunteers. Only after

such preliminary studies have been successfully concluded will proper clinical trials

be approved, which will then determine whether the drug or vaccine in question has

the desired clinical efficacy.

Because of the officially sanctioned haste and systematic gross negligence in

the development and approval of the COVID-19 vaccines, our knowledge of their

pharmacokinetics is sketchy. The only somewhat detailed animal study that has

reached the public pertains to the Pfizer vaccine [1, 2]. These data were publicized

after Pfizer had filed them with the Health authorities in Japan when applying for

emergency use authorization of its vaccine in that country.1 These data pertained

in particular to the distribution of the vaccine within the body after injection and to

its elimination from the body. Even though far from being comprehensive or even

adequate, this document has rather far-reaching implications: it shows that Pfizer—

as well as the authorities that were apprised of these data— must have recognized

the grave risks of adverse events after vaccination even before the onset of clinical

trials. Nevertheless, Pfizer’s own clinical trials failed to monitor any of the clinical

risks that were clearly evident from these data, and the regulatory authorities failed

to enforce proper standards of oversight. This dual failure has caused the most

grievous harm to the public.

...

4 Summary

Pfizer’s animal data clearly presaged the following risks and dangers:

• blood clotting shortly after vaccination, potentially leading to heart attacks,

stroke, and venous thrombosis

• grave harm to female fertility

• grave harm to breastfed infants

• cumulative toxicity after multiple injections

With the exception of female fertility, which can simply not be evaluated within the

short period of time for which the vaccines have been in use, all of the above risks

have been substantiated since the vaccines have been rolled out—all are manifest in

the reports to the various adverse event registries [9]. Those registries also contain

a very considerable number of reports on abortions and stillbirths shortly after

vaccination, which should have prompted urgent investigation.

We must emphasize again that each of these risks could readily be inferred from

the cited limited preclinical data, but were not followed up with appropriate indepth 

investigations. In particular, the clinical trials did not monitor any laboratory

parameters that could have provided information on these risks, such as those

related to blood coagulation (e.g. D-dimers/thrombocytes), muscle cell damage (e.g.

troponin/creatine kinase), or liver damage (e.g. γ-glutamyltransferase). That the

various regulatory agencies granted emergency use authorization based on such

incomplete and insufficient data amounts to nothing less than gross negligence.

Of particularly grave concern is the very slow elimination of the toxic cationic

lipids. In persons repeatedly injected with mRNA vaccines containing these lipids—

be they directed against COVID, or any other pathogen or disease—this would result

in cumulative toxicity. There is a real possibility that cationic lipids will accumulate

in the ovaries. The implied grave risk to female fertility demands the most urgent

attention of the public and of the health authorities.

Since the so-called clinical trials were carried out with such negligence, the real

trials are occurring only now—on a massive scale, and with devastating results.

This vaccine, and others, are often called “experimental.” Calling off this failed

experiment is long overdue. Continuing or even mandating the use of this poisonous

vaccine, and the apparently imminent issuance of full approval for it are crimes

against humanity.