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Saturday, August 14, 2021

Covid Roundup 8/14/21

Four items of interest.

First, Karl Denninger expands on some matters that--as I understand it--commenter Mikeyinfl has been talking up lately:  Well, ****.... In the excerpt that follows I present the technical part that KD quotes first, then go to KD's explanation of the significance. As I understand it, the significance is that ADE--Antibody-Dependent Enhancement is a very real thing with the Dread Delta. The result is that the Dread Delta is able to actually leverage vaccine originated antibodies for its own purposes:


I suspected this would occur....

Antibody dependent enhancement (ADE) of infection is a safety concern for vaccine strategies. In a recent publication, Li et al. (Cell 184 :1-17, 2021) have reported that infection-enhancing antibodies directed against the N-terminal domain (NTD) of the SARS-CoV-2 spike protein facilitate virus infection in vitro, but not in vivo. However, this study was performed with the original Wuhan/D614G strain. Since the Covid-19 pandemic is now dominated with Delta variants, we analyzed the interaction of facilitating antibodies with the NTD of these variants. Using molecular modelling approaches, we show that enhancing antibodies have a higher affinity for Delta variants than for Wuhan/D614G NTDs. We show that enhancing antibodies reinforce the binding of the spike trimer to the host cell membrane by clamping the NTD to lipid raft microdomains. This stabilizing mechanism may facilitate the conformational change that induces the demasking of the receptor binding domain. As the NTD is also targeted by neutralizing antibodies, our data suggest that the balance between neutralizing and facilitating antibodies in vaccinated individuals is in favor of neutralization for the original Wuhan/D614G strain. However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity. Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors).

You stupid, stupid bastards.....

Coronaviruses have a long history of doing this sort of thing and its one of the reasons we've never managed to have a vaccine developed for them before; it simply doesn't work.  

...

So here's what happened.

In mid-December, before the first person had full vaccinated immunity, cases were falling dramatically in the United States.

...

But we were stupid.

We jabbed a huge percentage of our population.  And as has occurred every other time with coronavirus vaccine attempts the virus mutated around the protection and in fact used the vaccine antibodies to enhance infection.  Delta is in fact promoted by those who were vaccinated.  As with all other Covid variants most people get a mild or no real illness, but some people get hammered.  However, prior infection doesn't help if you got jabbed since you took a drug that helps the virus attack you.  We created a third wave by our own stupidity: Stupidity seen in nation after nation, but only in nations with high vaccine prevalence; Israel, the UK, Iceland and here in the United States.


Woops!

At Legal Insurrection there's a timeline for Covid's development, dating back to 2003 with Chinese involvement in SARS Classic. However I'll excerpt the concluding portion that talks about what we can expect going forward:


What is the Future?

Reviewing the information above, I will project that:

  • China will continue its substandard biological safety practices at all facilities, including the 25-30 new ones it proposes building.
  • If there is an outbreak of any disease, new or otherwise, in the winter Olympics of 2022…China will not act to protect the athletes.
  • China will continue to deny any problems and hide any evidence connecting them to any significant safety issue of international concern.

In terms of what will happen with the SARS-Cov-2 pathogen that we are now battling, I think that the “Russian Flu” epidemic of 1889 provides some clues.  This is the first coronavirus pandemic that has been identified.

The history of that event indicates that the world will experience cycles of infections for the next several years.  Only when enough immunity is developed and less potent but more infectious variants arise will the current virus strain join the other coronaviruses causing common colds.  It is unlikely we will immunize, mask, or social-distance ourselves from the cyclic process.


In other words, the Swedish model appears to be the sensible approach. Contrary to the daft notion that the vaccines will somehow stop the spread and stop the mutating--neither will happen--natural spread and the normal process of mutation will be our ticket out of this. The vaccines simply induce ADE type mutations that leave large numbers of people more vulnerable than they would be otherwise.

Next up, a fascinating article that covers the subject of whether the vaccines can lead to alterations in human DNA. This is one of the topics anti-vaxxers commonly raise, and that just as commonly gets labeled as "disinformation" or "conspiracy theory". This article was published at an anti-vax site. The author is a doctor who also has a PhD in molecular biology. He argues that the reality, as so often, is more complicated that supposed. As usua,l I'm excerpting. Note that, while the title references J&J, the author goes on to discuss the mRNA vaccines, as well:


Why I Won’t Take the Johnson & Johnson Vaccine — a Scientist’s Perspective

Children's Health Defense ^ | 04/12/21 | Ken Biegeleisen, M.D., Ph.D.

...

No guarantees, despite what vaccine makers say

It seems that in many, perhaps most viral infections, integration of viral DNA into the host cells is a very real possibility. When this occurs, there is absolutely no way to “guarantee” that the genetic code of the host cell will not be re-written.

The question then arises: If this is the case, why do vaccine manufacturers “assure” us that their marginally tested products are genetically “safe?”

I would suggest three possible explanations, all equally reprehensible:

  1. It may be that the scientists in these companies simply do not know the history of this field. What can one say? “Those that fail to learn from history are doomed to repeat it.”
  2. It may be that anything in industry which does not improve the quarterly profit report is at great risk of being ignored.
  3. It may be that calling a new vaccine “safe,” in the pharmaceutical world, means little more than that the company has the legal resources to deal with any liability claims that arise.

Which of these three possible explanations is the correct one? Or is it all three?

In any event, you now know why I shall not take the Johnson & Johnson vaccine.

What about RNA vaccines?

We’ve been discussing DNA vaccines. What about RNA vaccines, such as Pfizer and Moderna?

Although I have no personal experience working in the lab on genetic transformation of human cells by RNA viruses, it is appropriate to comment briefly on that subject before closing.

The RNA vaccines are alleged by their promoters to be genetically “safe” because RNA cannot be directly incorporated into human chromosomes.

Is that true? Yes. But does that make them “safe?” Perhaps not.

What the vaccine companies forgot to tell you is that our cells have several types of “reverse transcriptase” of their own, which can potentially convert the vaccine RNA into DNA.

In December 2020, a team of researchers from Harvard and MIT (Zhang et al) posted an article at the Cold Spring Harbor Laboratory-hosted bioRxiv preprint server showing that, in all probability, incorporation of coronavirus spike protein genes, into the chromosomes of infected cells, does indeed take place, and is mediated by the so-called “LINE-1” type of human reverse transcriptase. (For more on the Harvard-MIT study and its implications, read this article previously published by The Defender).

To be clear, this was not a vaccine study, but a study in which cells were deliberately infected with whole, non-inactivated virus, as happens in nature, and which apparently can result in genetic transformation of the cells after all.

This, suggested the authors, may account for the now-frequent observation of COVID-19 test “positivity” in people who are clearly not sick. That is, the bodies of such people are continually manufacturing corona spike protein, from the viral genes which have been permanently incorporated into their genetic codes.

...

Moreover, reverse transcription is a known means of normal human chromosome-to-chromosome gene mobility, a fascinating process whose study goes back to the pioneering work of Barbara McClintock in the 1930s. It has thus been well-known, for the better part of a century, that the effects of moving genes around will very much depend on where they are moved, and on exactly and precisely what is moved.

...

..., we’re all being pressured into taking hastily prepared genetic vaccines, which are likely to transform our heredity, permanently. Is there any reason for this, other than countless billions of dollars in windfall profits?

...

Most sensible people are wary about “GMO,” even in food. Now we’re going to genetically modify ourselves? Why? What madness is this?


Finally, a new study published in the JAMA--the Journal of the American Medical Association (as mainstream as it gets)--appears to offer confirmation of a statement that Dr. Robert Malone made at the Liberty Forum. Malone briefly stated that he had reliably heard that cardio- side effects were much more common than the CDC has been letting on. That's exactly what this article is stating:


New Research Shows – Heart Inflammation After COVID Vaxx More Common Than CDC Claims


This article has a lot of information in it, so I'll just excerpt the bottom line as suggested by the title:


A new study published in JAMA shows 1 in 100,000 people had vaccine-related myocarditis and 1.8 in 100,000 people had pericarditis — compared to the CDC’s data that 4.8 people per 1 million suffer myocarditis after receiving a COVID vaccine.

U.S. public health officials claim cases of myocarditis and pericarditis following COVID vaccination are rare — but new research published online in the Journal of American Medical Association (JAMA) shows they may happen more often than reported.

Post-vaccine myocarditis and pericarditis also appear to represent two “distinct syndromes,” Dr. George Diaz, with the Providence Regional Medical Center Everett, told Medscape Cardiology.


Of note, the study suggests that the side effects are not associated with Covid the disease but, instead, with the injections:




8 comments:

  1. Just to dovetail what Mark has posted is an article that was reposted to Zerohedge. India's Ivermectin Blackout.

    Here's the link to the original story authored by an MD.

    https://www.thedesertreview.com/opinion/columnists/indias-ivermectin-blackout/article_e3db8f46-f942-11eb-9eea-77d5e2519364.html

    The premise is that Covid has been drastically diminished in India with the help of Ivermectin, yet no one has reported this to the world.

    The doctor gives some excellent examples of the Ministry of Truth suppression of information that might cause one to challenge the Obstreperous Vaccinators like Fauci et. al in their constant brow beating the public to do their "duty" and join in this great experiment.

    What's compelling about his observation is the comparison where all but one province in India are using Ivermectin and one is not with a marked difference in deaths (and also the almost meaningless cases count. What is also fascinating is the comparison of India with lower vaccination rates (well under 5-15% depending on province) and the USA with over 50% vaccination. Here's the info pasted from the article (note I changed the off Intermectin to NOT ON for emphasis):

    Uttar Pradesh ON Ivermectin: Population 240 Million [4.9% fully vaccinated]
    COVID Daily Cases: 26
    COVID Daily Deaths: 3

    The United States NOT ON Ivermectin: Population 331 Million [50.5% fully vaccinated]
    COVID Daily Cases: 127,108
    COVID Daily Deaths: 574

    Uttarakhand ON Ivermectin: Population 11.4 Million [15% fully vaccinated]
    COVID Daily Cases: 24
    COVID Daily Deaths: 0

    Here's the province NOT ON Invermectin:
    Tamil Nadu off Ivermectin: Population 78.8 Million [6.9% fully vaccinated]
    COVID Daily Cases: 1,997
    COVID Daily Deaths: 33

    Notice a trend besides the Ivermectin use attenuating the case/death count? Lower vaccination rate of course. Denninger also points this our between Israel which is highly vaxxed and Palestine which is not that much. Are the highly vaxxed groups generating more cases and deaths than those in the much lower range? Certainly looks like it. Does Ivermectin also help? Also looks that way. Just comparing Tamil Nadu which has a much larger count than all the provinces that are using Ivm, it's still dwarfed by the numbers in the USA. 39 deaths in total for 4 provinces that are combined about the same size as the USA with 574.

    Once Americans find this out, especially those who reluctantly got jabbed, I would expect a huge backlash against the regime. Hence the need to keep it all under wraps.










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  2. "The United States NOT ON Ivermectin: Population 331 Million [50.5% fully vaccinated]
    COVID Daily Cases: 127,108
    COVID Daily Deaths: 574"

    US daily deaths...574? 574???? What the #^#%@^@ are even talking about? A population of 340 million is obsessing over such puny numbers? No wonder the narrative had to be shaped from day one that one death is one too many. (Unless of course we're talking about people dying from the jab in which case it's insignificant and oh well and sacrifices must be made) Jq

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    1. Cases, Cases, the sky is falling. Panic Porn.

      As an aside to the aforementioned article, I wanted to verify some of the numbers that were quoted just to be sure. I went to the JHU-CSEE board with the world map and did in fact find similar numbers just by manually following some of the Indian provinces he used. I probably could have downloaded the data and spent hours sifting, but this was close enough to convince me he's spot on. I simply used the 28 day tab at the bottom and did simple division for the daily count.

      Uttar Predesh
      Cases 1096 -> 39.1/day
      Deaths 68 -> 2.42/day

      Tamil Nadu
      Cases 53,562 -> 1912.9/day
      Deaths 801 -> 28.6/day

      USA
      Cases 2,572,359 -> 91,876/day
      Deaths 12486 -> 445.9/day

      Of course this all depends on accurate data reporting, but even so. Look at the orders of magnitude difference. Toady as I've come to call him, has led us down a dark hole and if you read Denninger's post this morning citing the study from Vietnam on 69 vaccinated healthcare workers testing positive for Covid and seem to have spread it amongst themselves, it's eye opening to say the least. Thankfully, all recovered, but what's even more shocking is these breakthrough cases had viral loads 251X higher that seen the previous year on the Alpha strain (yes, 251x). Think of all the healthcare mandates going into place and what happens when hospital staff are now billowing huge amounts of Delta while working with patients. From the report:

      "The absence of correlation between neutralizing antibody levels and peak viral loads suggested that vaccine might not lower the infectivity of breakthrough cases."

      https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3897733

      https://market-ticker.org/akcs-www?post=243270

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  3. As much as i appreciate the updates and Denninger and Malone et al...I am almost at the point where I just want to say, Get on with it already and just tell us that the jab really is an evil plan to depoulate the world so the lizard lords can bring their lizard families to earth and enjoy spacious living in Manhattan and LA without human parasites to interfere. Can we just cut to the chase and get the worst out in the open all at once? It's like a bad novel where you can see where it's going and taking waaaay too long to get there. Let me skip to Chapter 88 already. Yeesh.

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  4. This fraud simply cannot be maintained forever, and it's looking like not very much longer, like can't make it to September. Simple common sense, which we all have whether we choose to use it or not, tells us that the same "authorities" who are telling us this is an unprecedented deadly pandemic which we must drop EVERYTHING else in the world to fight and such that EVERYONE must get the experimental gene therapy or we're going to die, and further to the point of pushing the experimental gene therapy on CHILDREN even before FDA approval (which they will never get without fraud or revealing something like the real trials results thus far of these trials THUS FAR, these same authorities publish lethality statistics of the virus itself which are miniscule in comparison to the rhetoric. Employers who "mandate" an experimental gene therapy are not even on shaky legal ground, they're on no legal ground. As demands for Informed Consent and adherence to the Nuremberg Code grow these criminals (at the top) will have an increasingly hard time finding willing injectors on the ground. In fact, it would seem fairly straightforward for any of us unjabbed to simply push back even a little bit and these petty tyrants doing the bidding of these criminals will fold like cheap suits. Who decided to vax the children and when did they decide it? Let's start with that one. Mark A

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  5. Mark,
    Many thanks as always - we share with our friends, all takers (both 'sides'), but the only folks who thank us are similarly questioning the regime and establishment views (take the vaccine, COVID is a deadly pandemic without treatment, don't question, wear masks).
    We seem to be leaving an entire possibility off the table in our dialogs - we know of mask mandates, and the 'other option' of mask optional (which is akin to the ban on mask mandates) - but that's not really the other end of the spectrum; we need to be clear and offer the other option is to actually have a no-mask mandate. A stronger gov't official/polit might actually score points by prohibiting any masks, and arguably there is sufficient data/science/studies of the harmful effects of masking vis a vis the minor/minimal benefits that a gov't decision to ban masks would likely pass judicial review. or at least give cover for the state ban. Let's try that for a period - we do that in other contexts (if you like it now when you're in control don't forget you won't always be and how will it play out when you cannot wear a mask?).
    which then begs the Q - are people fleeing the week states for those that have the mask bans? we all know the media wouldn't report if it happened, but even among us is anyone doing it yet? we live in Ga and have a weak Gov, but 3 of surrounding states have done it (only SC hasn't) and we are considering it, if it is working to keep schools and employers from enacting vacc mandates, time will tell here, as news is out some local school boards are defying the gov ban, but shouldn't that be a slam-dunk for the Governors?
    Mark - can I ask given your Catholic faith, our archd here has said in its most recent announcement that everyone should get the vacc unless there is a medical reason not to; they are explicitly denying a right to a religious exemption - if I go to church under that position, seems I'm condoning and accepting that, which I don't, time to withdraw, not attend and hold back my support in all ways possible no?
    keep it up, please - 'you're our only hope....'
    Tom

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    1. It's tough. You should be looking for alternatives. New parish, whatever it takes. The faith is the faith, but you need a place where the faith is upheld.

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  6. To this day, doctors are telling patients there is no large, peer reviewed study showing ivermectin is effective.
    100s of millions of Indians seems a large enough test group group to me.

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