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Tuesday, July 27, 2021

News/Not News?

You be the judge.

The other day, in the post regarding the Dr. McCullough interview, I suggested that the findings that appeared to associate specific vaccines with specific variants might be a signal that ADE (Antibody Dependent Enhancement) might be occurring. For example, the Dread Delta variant appears to be associated with the Sinovac vaccine, whereas the new Epsilon variant in California is associated with Pfizer, Moderna, and J&J. By "associated with" I mean that these vaccines promote the variants or mutations by pushing the virus to mutate in a particular direction. It's a bad thing--you prefer to have random mutations, which tend in a more benign direction. This is how Wikipedia explains ADE, just to refresh your recollection:


Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication.[1][2] ADE may cause enhanced respiratory disease and acute lung injury after respiratory virus infection (ERD) with symptoms of monocytic infiltration and an excess of eosinophils in respiratory tract.[3] ADE along with type 2 T helper cell-dependent mechanisms may contribute to a development of the vaccine associated disease enhancement (VADE), which is not limited to respiratory disease.[3] Some vaccine candidates that targeted coronaviruses, RSV virus and Dengue virus elicited VADE, and were terminated from further development or became approved for use only for patients who have had those viruses before.


I'm not a scientist, so I'm not in a position to say that ADE plays into the rise of the various variants. However, here's a tweet by Dr. Robert Malone. He's citing data reporting from the Israeli Ministry of Health. As I read his tweet, he's suggesting that the data may be signaling that ADE is a factor:



Again, a reminder. People like Yeadon and Bhakdi (and others) have been warning that "vaxxing" during a pandemic is precisely what will lead to ADE coming into play. The point is, ADE will place those who have been "vaxxed" at greater risk. In other words, it's not the unvaxxed creating the increased risk, it's the "vax" that's creating the increased risk.

Now, consider this new article by a statistician. It's recommended by Malone for anyone who thinks that our government would never hide from us true information that's important for our health and safety. The author examines the math behind the CDC's methodology for examining VAERS data on "adverse event" data reporting for Covid. The point is to determine whether the methodology is adequately designed to identify "vaccine" safety or, from the opposite standpoint, to identify safety issues. Not only am I not a scientist, I'm not a math guy, either. However, Malone is conversant enough with math and science that I'm willing to accept his judgment that the author is making an important point.


Defining Away Vaccine Safety Signals


Will start with the author's definition of the issue, just so you can see whether I framed it correctly:


What if it turns out that vaccines are killing and crippling millions of people around the world, but that those harmed are just well enough spread out that almost nobody saw sufficient signals to build an intuition about the problem? And what if the agency most responsible for examining safety signals defines their algorithm using a nonsensical mathematical formula that hides nearly all serious problems?


My conclusion is that if this is the case, we have a major problem on our hands.

The author next discusses the importance of definitions in any mathematical or statistical undertaking. His point is simple: If the definitions are nonsensical, the statistical feedback will also be nonsensical. Importantly, he draws attention to the fact that reporting procedures for VAERS were changed for Covid:


To a mathematician, everything depends on definitions. Whatever we state mathematically, the definitions of the terms we use should be traceable back to the axioms of the field we're working in. ... No mathematician or statistician with a soul forgets the well from which they draw energy and meaning. 

What we don't do ... is lackadaisically establish definitions entirely ill-suited to a purpose. ...

Adverse Events and Safety Signals

During the past few months, many people (including myself) have learned for the first time about the Vaccine Adverse Event Reporting System (VAERS) where health care workers and patients can submit adverse events (AEs) suffered post-vaccination. While the VAERS database is understood to record an often small subset of the AEs, the information can still be used for purposes of establishing safety signals. A new influenza vaccine can be compared to other influenza vaccines, for instance. If the old ones were safe enough, and the reported AEs of a new one are in line or better than for past vaccines, then the risk-benefit analysis for the new vaccine (assuming sufficient efficacy) either remains the same or improves.

As with a great deal of health care regulation during the declared pandemic, changes were made to the VAERS system and also to safety signal analysis leading up to the experimental mass vaccination program officially targeting COVID-19.


The author draws attention to a statement that the CDC made in revising the VAERS system. Specifically, the CDC stated that it would be generating weekly reporting tables, but that it would not make those tables publicly available. That decision is baffling to say the least.

The author next discusses the math behind the proportional reporting ratio (PPR). I'm not qualified to discuss that, so I'll skip to his conclusions. He finds the methodology absurd, totally at odds with the purported goals, and then raises the interesting question: Was this have been the result of rank incompetence or could it have been by design?


Do you kinda get the sense that the PRR function is designed to hide signals of unsafe vaccines, not to identify them?

Maybe this is a matter of incompetence?

Hanlon's razor: never attribute to malice that which is adequately explained by stupidity.

There is no doubt that governments are jam packed with incompetent people in important roles (often scattered around a handful of brilliant ones who unfortunately lend their credibility). ...

However, Hanlon's razor is one of the most oversubscribed principles of human interaction. A firm belief in its truth is an invitation for con artistry. Wherever there are concentrations of money or power, we should expect to find the fully manifest game theory of hawks and doves. 

At some point, when the potential for conflicts of interest are high and the point of failure is fundamental to the task of those doing the job, incompetence should no longer be differentiated from criminal intent. Mathematicians and statisticians worthy of the title do not miss the kind of scale invariance or mean-reversion we see embedded in the PRR---particularly not when working in a dedicated group on a serious problem. There is a pride among geeks in identifying subtle mathematical or logical flaws in a system, and this is not subtle at all. Given that even psychologists have a need to pay attention to scale invariance, this is not an easily excused mistake. In fact, a computational check of the PRR function against past data likely would have clued in a middling programmer without the fundamental mathematical training. And we're not done, yet…


OK, this next passage gets to the heart of things, but is technically dense--look to the conclusion again:


Let's look back at the definition of a safety signal (emphasis mine):

A safety signal is defined as a PRR of at least 2, chi-squared statistic of at least 4, and 3 or more cases of the AE following receipt of the specific vaccine of interest.  

Not only does the PRR need to get out of line for a safety signal to be generated, the use of 'and' instead of 'or' means that other additional criteria must also be satisfied before the CDC self-reports a safety signal! And the chi-squared criterion isn't helping the situation. Those unfamiliar with statistics will not recognize the problem, but when the different vaccines all result in similar problems (like myocarditis or blood clots, as has been noted), the chi-squared statistics will remain muted. In fact, chi-squared statistics are not even supposed to be used on data that is likely to be correlated when causal. Presumption of a negative test result is not a reasonable test standard. It's as if nobody at all thought about the possibility that the spike protein being an underlying thread among the vaccines could possibly be important. 

So, when you define away the problems on paper, they just cease to exist?

Calling this a safety system is decidedly unsafe.


In other words, the author is asserting that this is, in fact, a system that is a result of either incompetence or criminal intent. Let that sink in. That's a serious charge to put your name to. And so he concludes:


If my understanding of this situation is correct, the mass vaccination program should be immediately halted until the safety data is gathered, cleaned, and examined. We cannot tolerate a misleading statement of "vaccines are safe and effective" in the face of regulatory agencies defining away the responsibility of performing the risk analysis needed to verify safety. The CDC leadership should be immediately replaced and investigated, and independent analysts should reformulate the task of tracking vaccine safety results.

I really hope I've misinterpreted something. I stumble over ideas and make mistakes just like everybody else. Unlike the CDC, I'd like for you to share my numbers widely and invite critique. ...

I'd rather be a little embarrassed in the eyes of many if I'm wrong than to watch even one more person get sick or die and perhaps become another false COVID statistic.


Unfortunately, the last four or five years have given us no reasons to trust our government. These considerations take on added importance as the very real prospect of coercive "vax" policies increases.


10 comments:

  1. All this is why that Deagle.com prediction remains fixed in my head: ”70% reduction in U.S. population by 2025”.

    Boarwild

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  2. "In other words, the author is asserting that this is, in fact, a system that is a result of either incompetence or criminal intent."...

    In the years I worked in business processes around accounting there was a hard learning curve on incompetence vs evil intentions. Very often you would find yourself saying "they can't be THAT stupid"... Truth is, yeah they can.

    I'm certainly not defending the situation but the majority of our government functions on the lowest common denominator pulling the trigger on most subjects. Ignorance is bliss!

    Dunning Kruger is a VERY real thing. https://www.verywellmind.com/an-overview-of-the-dunning-kruger-effect-4160740

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  3. Certainly related, Sundance has started connecting
    some interesting dots - the major push for mandatory vaccinations by Chairman Xiden. CDC and the band of global miscreants.

    https://theconservativetreehouse.com/blog/2021/07/26/the-alinsky-play-is-clear-california-state-joins-new-york-city-and-veterans-administration-in-mandating-vaccination-shots-for-employees-simultaneous-to-cdc-changing-covid-test/

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  4. I've brought this up before but I'm repeating it now anyway: my rejoinder to the whole "don't blame malice when incompetence can explain things" is my old adage that "only dumb people let smart people get away with playing dumb."

    Bet on those latter words every time and you'll almost never lose.

    If the intentions of the people behind the VAERS/Covid policy were pure, they wouldn't be keeping so many secrets. They are in fact plenty smart people trying like crazy to convince people they're stupid, since it beats the hell out of the people concluding the truth - which is that they're in fact just evil, with the basest of intentions.

    Sorry if that's a little strong, but all they have to do to avoid the charge is end the secrecy, the censorship and the lies - the combination of which has killed countless thousands with no end in sight (not to mention the even greater sin of the damage they're doing to our American system of self-government).

    Until then, I stand firm.

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    1. Great comment, Brad. I agree 100%. Regardless of the intent of its component actors, if the net effect of a process is negative (unsuccessful), that process needs to be analyzed and corrected. To do that you need reliable controls and metrics. We have not had those provided by the CDC or FDA or NIH. Why not? If these organizational policies and procedures are not open to analysis and are not amenable to correction, they cannot be considered either scientific or legitimate. That is where we are at. Trust the science? Yeah... if it is arrived at scientificly.

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    2. I'm with you guys. Having worked for government all my adult life until retirement, I'm not inclined to discount sheer incompetence. Nevertheless, it would be foolish to make that your default choice. IMO, the higher you go, the more likely to encounter outright dishonesty.

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  5. Denninger today, in "Ruin Them", on jab upshots:

    < It may well be true that originally, over the first couple of months, you have some level of protection -- perhaps even very good protection.
    But on the data, that protection appears to rapidly wane, and it appears that within *six months*, it can turn into potentiating infection, instead via OAS, ADE or both.
    In other words, the data suggests you get protection originally, but then get screwed compared against where you were when you started, which would suit the makers of the jabs just fine, yes?
    How will you like it, if you wind up dependent on continuous "boosters", at whatever price they want to charge forever, lest you be screwed instead of helped.

    If you want to know why that would be hidden, other than the obvious -- that they simply will never admit they failed, and you're being cajoled or coerced into taking a dangerous drug, that in the intermediate term has damaged your immune system -- that should be obvious, as it opens up a *legal* attack avenue against any such mandate, in health care or otherwise, that you can drive a truck through.
    Oh, and the makers of said jabs were given legal immunity from this outcome too; if accepting the first of the jabs turns you into a *junkie*, permanently dependent on repeated jabs to stave off disease, which otherwise becomes more likely, as a direct result of accepting the original shots, you cannot sue Pfizer, Moderna or J&J.

    Further, however, and far more importantly, is the fact that, with the emerging evidence on Ct reports from so-called "breakthrough" cases, it is becoming very clear, that vaccinated people in health care settings are actively dangerous, as if and when they get a breakthrough case, they will be more *likely to spread* the virus to others, as their infected state will not be known, as *rapidly and reliably* as with someone who has not been vaccinated, and by the point of detection, their *viral load* will be materially higher.

    This is exactly what occurred in the early months, where health care workers were *the vector* into vulnerable people, and killed them. We knew this was a risk, and refused to isolate health care workers from the general population.
    It is now clear, that this is very likely to happen again, but this time is being "boosted" by the jabs. Indeed there is a clean argument, that being jabbed against this virus should be banned, among those working in a health care environment, since an infected person with a *lower Ct* number is much more-infectious, than someone with a higher one.
    The viral load, and thus capacity to transmit the virus, *doubles with each* lower Ct! If the jabs make it more-likely, that you will not develop symptoms until you have a lower Ct value, then they make you more-dangerous to others, irrespective of whether they prevent your mortality.... >

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    Replies
    1. @ananymouse, do you have a link please?

      Frank

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    2. @nany, never mind, I found it.

      How many sites does this guy have?

      Frank

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    3. He has his regular site, and a separate one ( https://market-ticker.org/akcs-www?blog=Market-Ticker-Nad ) w/o ads, for posts that might trigger censors.

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